1¡¢She                        to become an astronaut, which I could understand. After all, it is a                  profession. (desire)

2¡¢He is a               leader, which              our developing direction. His                   surely leads to a good result. (determine)

3¡¢The                    were busy dealing with all the necessary                 . (procedure, astronaut)

4¡¢You can try                    (take)the medicine; it may work.