第二部分：英语知识运用(共两节，满分45分)
第一节、单项填空(共15小题，每小题1分，满分15分)
从A、B、C、D四个选项中，选出可以填入空白处的最佳选项，并在答题卡上将该项涂黑。
--- _____________.
A. It’s my pleasure B. Not to mention it
C. Mind your own business D. You’re welcome
22. After the quarrel, I tried all my best to fix the misunderstanding between us, but all my efforts seemed ______.
A. in trouble B. in case C. in time D. in vain
